| 规格: | 98% |
| 分子量: | 349.36 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 25mg | 电议 |
Background:
KIT inhibitor; inhibits phosphorylation of KIT, STAT3, STAT5 and Akt. Suppresses proliferation of OCI/AML3 cells (IC50 = 175 nM). Caspase-dependant apoptosis inducer.
Faderl et al (2009) Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer Res. 69 3910 PMID:19383925
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