(E)-10-Hydroxynortriptyline(E-10-OH-NT)是Nortriptyline的代谢物。Nortriptyline是三环类抗抑郁药，是Amitriptyline的主要活性代谢物，用于缓解抑郁症状。
货号:ajcx29804
CAS:47132-16-1
分子式:C19H21NO
分子量：279.38
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline . Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8. [2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.