IDT307 是有机阳离子 MPP+ 的类似物，是 DAT 的荧光底物 (荧光底物 APP+)。
货号:ajcx32550
CAS:1141-41-9
分子式:C14H17IN2
分子量：340.2
溶解度:DMSO : 62.5 mg/mL (183.72 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].

IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine[1].IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse[1].

参考文献:
[1]. Tao Hu, et al. Molecular mechanisms of organic cation and anion transport at the blood‐CSF barrier. 01 April 2018.