Methyl 5-hydroxypyridine-2-carboxylate 是一种酚酸，存在于 Mahonia fortune 的茎中。 Methyl 5-hydroxypyridine-2-carboxylate 在体外表现出 NO 抑制活性。
货号:ajcx33158
CAS:30766-12-2
分子式:C7H7NO3
分子量：153.14
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro[1].

Methyl 5-hydroxypyridine-2-carboxylate (compound 2) inhibits NO in LPS-stimulated RAW264.7 and BV2 cells, with IC50s of 115.67 and 118.80 μM, respectively[1].Methyl 5-hydroxypyridine-2-carboxylate (6.25-200?μM) does not exhibit any cytotoxic effect[1].

[1]. Liu L, et, al. Simultaneous characterisation of multiple Mahonia fortunei bioactive compounds in rat plasma by UPLC-MS/MS for application in pharmacokinetic studies and anti-inflammatory activity in vitro. J Pharm Biomed Anal. 2020 Feb 5;179:113013.
[2]. Liu L, et, al. Simultaneous characterisation of multiple Mahonia fortunei bioactive compounds in rat plasma by UPLC-MS/MS for application in pharmacokinetic studies and anti-inflammatory activity in vitro. J Pharm Biomed Anal. 2020 Feb 5;179:113013.