Omiganan 是一种阳离子抗菌肽。Omiganan 作为吲哚啶的类似物，对革兰氏阳性菌和革兰氏阴性菌均有抑制作用，对念珠菌也有抑制作用。Omiganan 可以用于酒精鼻和痤疮的研究。
货号:ajcx35712
CAS:204248-78-2
分子式:C90H127N27O12
分子量：1779.15
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne[1][2].

Omiganan results in a statistically significantly reduction in bacterial counts. omiganan reduces the bacterial counts by 3.8 (S. aureus), 2.2 (S. epidermidis) and 2.3 (C. albicans) log10 CFU/site. Omiganan has rapid bactericidal and fungicidal properties and significant dose-dependent activity against a broad spectrum of infected organisms[2].

[1]. Faccone D, et al. Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates. Eur J Med Chem. 2014;71:31-35.
[2]. Rubinchik E, et al. Antimicrobial and antifungal activities of a novel cationic antimicrobial peptide, omiganan, in experimental skin colonisation models. Int J Antimicrob Agents. 2009;34(5):457-461.