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Eribulin-d3 mesylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eribulin-d3 mesylate图片
包装:1mg
规格:98%
市场价:95256元
分子量:829.02

产品介绍
Eribulin-d3 mesylate 是 Eribulin mesylate 的氘代物。Eribulin mesylate 是靶向微管 (microtubule) 的抗癌剂,可用于研究癌症。
货号:ajcx36470
CAS:N/A
分子式:C41H60D3NO14S
分子量:829.02
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Eribulin-d3 mesylate is a deuterium labeled Eribulin mesylate. Eribulin mesylate is a microtubule targeting agent that is used for the research of cancer[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et, al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. Watanabe K, et, al. Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo. Oncotarget. 2019 Jan 4;10(2):161-174.