Batatasin III 是一种芪类化合物，通过抑制上皮间质转化 (EMT) 和FAK-AKT 信号来抑制癌症迁移和侵袭。Batatasin III 具有抗癌活性。
货号:ajcx37496
CAS:56684-87-8
分子式:C15H16O3
分子量：244.29
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Batatasin III, a stilbenoid, inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition (EMT) and FAK-AKT signals. Batatasin III has anti-cancer activities[1].

Batatasin III (25-100 μM; 48 h) exhibits anti-proliferative activity in H460 cells. Batatasin III at concentrations lower than 100 μM has no cytotoxic effects[1]. Batatasin III significantly suppresses EMT indicated by the decrease of N-cadherin and Vimentin, and up-regulation of E-cadherin[1].

[1]. Tatchakorn Pinkhien, et al. Batatasin III Inhibits Migration of Human Lung Cancer Cells by Suppressing Epithelial to Mesenchymal Transition and FAK-AKT Signals. Anticancer Res. 2017 Nov;37(11):6281-6289.