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PF-3644022
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF-3644022图片
CAS NO:1276121-88-0
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

PF-3644022 (PF3644022) is a novel, potent, selective, orally bioactive, and ATP-competitive inhibitor of mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) with anticancer activity. It inhibits MAPK2-MK2 with an IC50 of 5.2 nM and a Ki of 3 nM. PF-3644022 inhibits tumor necrosis factor α (TNFα) production in U937 monocytic cells and peripheral blood mononuclear cells (PBMCs) (IC50 = 160 nM).

纯度:≥98%

CAS:1276121-88-0