Amino-PEG9-acid 是一种 PROTAC 连接桥，属于 PEG 类。Amino-PEG9-acid 可用于合成一系列 PROTAC 分子。Amino-PEG9-acid 是一种不可降解 (non-cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
货号:ajcx38226
CAS:1191079-83-0
分子式:C21H43NO11
分子量：485.57
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Amino-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG9-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Iwaoka E, et al. Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1469-72.