Urelumab 是一种人源化的 IgG4 单克隆抗体，用作 CD137 激动剂，可增强 T 细胞和自然杀伤细胞的抗肿瘤活性，并增强 Rituximab 的细胞毒活性。Urelumab可用于弥漫性大B细胞淋巴瘤 (DLBCL)、滤泡性淋巴瘤 (FL) 和其他类型的非霍奇金淋巴瘤 (NHL) 的研究。
货号:ajcx39702
CAS:934823-49-1
分子式:N/A
分子量：N/A
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Urelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity, and may enhance cytotoxic activity of Rituximab. Urelumab can be used for the research of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL)[1].

[1]. John Timmerman, et al. Urelumab alone or in combination with rituximab in patients with relapsed or refractory B-cell lymphoma. Am J Hematol. 2020 May;95(5):510-520.