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HS79
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
HS79图片
规格:98%
分子量:338.47
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
HS-79是Fasnall的一种对映体,Fasnall是一种选择性脂肪酸合酶(FASN)抑制剂。HS-79能够抑制氚化乙酸盐掺入脂质中,IC50为1.57μM。
货号:ajcx13034
CAS:2138838-56-7
分子式:C19H22N4S
分子量:338.47
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].


[1]. Alwarawrah Y, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88.