CYN 154806 (TFA) 是一种环状八肽，是一种强效的选择性生长抑素 sst2 受体的拮抗剂，其对人重组 sst2、sst1、sst3、sst4 和 sst5 受体的 pIC50 值分别为 8.58、5.41、6.07、5.76 和 6.48。
货号:ajcx13830
CAS:N/A
分子式:C58H69F3N12O16S2
分子量：1311.36
溶解度:H2O: 50 mg/mL (38.13 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CYN 154806 (TFA), a cyclic octapeptide, is a potent and selective somatostatin sst2 receptor antagonist, with pIC50 values of 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively[1][2]. Somatostatin Receptor[1].

[1]. Bass RT, et al. Identification and characterization of novel somatostatin antagonists. Mol Pharmacol. 1996 Oct;50(4):709-15. [2]. Feniuk W, et al. Selective somatostatin sst(2) receptor blockade with the novel cyclic octapeptide, CYN-154806. Neuropharmacology. 2000 Jun 8;39(8):1443-50.