FLP 62064 是一种有效的5-脂氧合酶 (5-LOX) 和 COX-2 双重抑制剂。FLP 62064 具有有效的抗炎活性。
货号:ajcx15808
CAS:103141-09-9
分子式:C16H15N3O
分子量：265.31
溶解度:DMSO: 250 mg/mL (942.29 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

FLP 62064 is a potent 5-lipoxygenase (5-LOX) and COX-2 dual inhibitor. FLP 62064 has potently anti-inflammatory activity[1][2].

[1]. Blackham A, et al. FPL 62064, a topically active 5-lipoxygenase/cyclooxygenase inhibitor. Agents Actions. 1990 Jun;30(3-4):432-42. [2]. Shabaan MA, et al. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase. Arch Pharm (Weinheim). 2020 Feb 7:e1900308.