LYN-1604 dihydrochloride 是一种有效的 UNC-51 样激酶 1 (ULK1) 激活剂，EC50 值为 18.94 nM。LYN-1604 可用于三阴性乳腺癌 (TNBC) 的研究。
货号:ajcx16730
CAS:2310109-38-5
分子式:C33H45Cl4N3O2
分子量：657.54
溶解度:DMSO: 50 mg/mL (76.04 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC)[1].

[1]. Zhang L, et al. Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo. Chem Sci. 2017 Apr 1;8(4):2687-2701.