Bz-RS-iSer(3-Ph)-OMe (compound 2) 是紫杉醇衍生物，在低细胞毒性下抑制 HSV 复制周期，阻断 Vero 细胞的有丝分裂，影响 M-MSV 诱导的肿瘤大小，并通过抑制 PHA 诱导的 T 淋巴细胞增殖而影响免疫应答。
货号:ajcx17210
CAS:32981-85-4
分子式:C17H17NO4
分子量：299.32
溶解度:DMSO: 130 mg/mL (434.32 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1].

[1]. Krawczyk E, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005;57(6):791‐797.