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PtdIns-(4,5)-P2(1,2-dipamitoyl)-d62(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PtdIns-(4,5)-P2(1,2-dipamitoyl)-d62(sodium salt)图片
规格:98%
分子量:1099.3
包装与价格:
包装价格(元)
25ug电议
50ug电议
100ug电议

产品介绍
PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) contains 62 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, 6', 7, 7', 8, 8', 9, 9', 10, 10', 11, 11', 12, 12', 13, 13', 14, 14', 15, 15', 16, 16, and 16 positions of each fatty acyl chain.
货号:ajcx18942
CAS:N/A
分子式:C41H16D62O19P3•3Na
分子量:1099.3
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) contains 62 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, 6', 7, 7', 8, 8', 9, 9', 10, 10', 11, 11', 12, 12', 13, 13', 14, 14', 15, 15', 16, 16, and 16 positions of each fatty acyl chain. It is intended for use as an internal standard for the quantification of PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) by GC- or LC-mass spectrometry. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-4,5-P2-(1,2-dipalmitoyl)-d62 is a synthetic analog of natural PtdIns containing deuterated C16:0 fatty acids at the sn-1 and sn-2 positions. This synthetic standard features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of phosphatidylinositol 4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.