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Somatostatin-28(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Somatostatin-28(trifluoroacetate salt)图片
包装:500ug
规格:98%
市场价:2170元
分子量:3148.6

产品介绍
Somatostatin-28 is a cyclic neuropeptide hormone that has a role in endocrine regulation.
货号:ajcx18988
CAS:N/A
分子式:C137H207N41O39S3•XCF3COOH
分子量:3148.6
溶解度:Formic Acid: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Somatostatin-28 is a cyclic neuropeptide hormone that has a role in endocrine regulation. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.60, 0.12, 0.22, 0.83, and 0.41 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 5.13, 1.91, 6.46, 2.95, and 3.55 nM, respectively). Somatostatin-28 stimulates growth hormone (GH) release from primary porcine pituitary cells when used at a concentration of 1 fM. It inhibits acid secretion induced by gastrin I and IBMX in isolated rat gastric mucosa (EC50s = 27 and 252 nM, respectively). In vivo, somatostatin-28 dose-dependently increases basal and pentagastrin-induced gastric acid secretion in rats.