A neuropeptide with diverse biological activities
货号:ajcx20782
CAS:1322626-74-3
分子式:C28H37D10NO4S • HCl
分子量：540.3
溶解度:aqueous base: slightly soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Tiamulin-d10 is intended for use as an internal standard for the quantification of tiamulin by GC- or LC-MS. Tiamulin is a pleuromutilin antibiotic.1 It is active against M. gallisepticum, M. synoviae, M. iowae, M. hyopneumoniae, M. hyosynoviae, M. hyorhinis, M. bovis, and M. agalactiae (MICs = 0.0025-0.25 μg/ml). Tiamulin is also active against various Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA).2 Tiamulin binds to the peptidyl transferase in the 50S ribosomal subunit to inhibit protein synthesis. Formulations containing tiamulin have been used in the treatment of veterinary enteric diseases and enzootic pneumonia.

|1. Hannan, P.C.T., Windsor, G.D., de Jong, A., et al. Comparative susceptibilities of various animal-pathogenic mycoplasmas to fluoroquinolones. Antimicrob. Agents Chemother. 41(9), 2037-2040 (1997).|2. Wilson, D.N. The A-Z of bacterial translation inhibitors. Crit. Rev. Biochem. Mol. Biol. 44(6), 393-433 (2009).