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Taurochenodeoxycholic Acid-d4(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Taurochenodeoxycholic Acid-d4(sodium salt)图片
规格:98%
分子量:525.7
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of taurochenodeoxycholic acid
货号:ajcx23554
CAS:2410279-85-3
分子式:C26H40D4NO6S.Na
分子量:525.7
溶解度:DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 3 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Taurochenodeoxycholic acid-d4is intended for use as an internal standard for the quantification of taurochenodeoxycholic acid by GC- or LC-MS. TCDCA is a taurine-conjugated form of the primary bile acid chenodeoxycholic acid .1Serum levels of TCDCA increase approximately 5-fold within two hours and begin to decrease within four hours during an oral lipid tolerance test in humans.2Serum levels of TCDCA are increased in patients with liver cirrhosis and may serve as a marker of disease progression.3


1.Hoffman, A.F.The continuing importance of bile acids in liver and intestinal diseaseArch. Intern. Med.159(22)2647-2658(1999) 2.Schmid, A., Neumann, H., Karrasch, T., et al.Bile acid metabolome after an oral lipid tolerance test by liquid chromatography-tandem mass spectrometry (LC-MS/MS)PLoS One11(2)e0148869(2016) 3.Wang, X., Xie, G., Zhao, A., et al.Serum bile acids are associated with pathological progression of hepatitis B-induced cirrhosisJ. Proteome Res.15(4)1126-1134(2016)