An internal standard for the quantification of norethindrone
货号:ajcx24614
CAS:2376036-05-2
分子式:C20H20D6O2
分子量：304.5
溶解度:Chloroform: slightly soluble,Methanol: slightly soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Norethindrone-d₆is intended for use as an internal standard for the quantification of norethindrone by GC- or LC-MS. Norethindrone is a synthetic progestin.¹In vivo, norethindrone (0.5 mg/animal per day) inhibits the estrous cycle in female mice. It induces tumor progression and metastasis in a BT474 breast cancer mouse xenograft model.²Formulations containing norethindrone have been used as oral contraceptives.

1.Bruce, H.M.Preliminary note on the effect of 19-norethisterone on mating behavior and fertility in the mouseProc. Soc. Study Fertility10158-165(1958) 2.Liang, Y., Benakanakere, I., Besch-Williford, C., et al.Synthetic progestins induce growth and metastasis of BT-474 human breast cancer xenografts in nude miceMenopause17(5)1040-1047(2010)