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L-Serine-d7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Serine-d7图片
规格:98%
分子量:112.1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
An internal standard for the quantification of L-serine
货号:ajcx25872
CAS:935275-35-7
分子式:C3D7NO3
分子量:112.1
溶解度:Water: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:


L-Serine-d7 is intended for use as an internal standard for the quantification of L-serine by GC- or LC-MS. L-Serine is a non-essential amino acid.1It is produced from 3-phosphoglycerate in a multistep biosynthesis catalyzed by phosphoglycerate dehydrogenase (PGDH), phosphoserine aminotransferase (PSAT), and phosphoserine phosphatase (PSP). L-Serine can also be derived from dietary sources, as well as protein and phospholipid turnover. Defective L-serine biosynthesis is associated with neural tube defects and deoxysphingolipid accumulation in patients with Neu-Laxova syndrome, a rare disease characterized by a mutation inPGDH.1,2Dysregulation of L-serine phosphorylation is associated with disease progression in patients with neurodegenerative diseases, including Alzheimer’s disease and amyotrophic lateral sclerosis.


1.Holm, L.J., and Buschard, K.L-serine: A neglected amino acid with a potential therapeutic role in diabetesAPMIS127(10)655-659(2019) 2.Metcalf, J.S., Dunlop, R.A., Powell, J.T., et al.L-serine: A naturally-occurring amino acid with therapeutic potentialNeurotox. Res.33(1)213-221(2018)