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10,11-dihydro-10,11-dihydroxy Carbamazepine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
10,11-dihydro-10,11-dihydroxy Carbamazepine图片
规格:98%
分子量:270.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
A metabolite of carbamazepine and oxcarbazepine
货号:ajcx26560
CAS:35079-97-1
分子式:C15H14N2O3
分子量:270.3
溶解度:DMSO: soluble,Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

10,11-dihydro-10,11-dihydroxy Carbamazepine is a metabolite of the anticonvulsant carbamazepine and the antiepileptic prodrug oxcarbazepine .1It is formed from carbamazepineviaa carbamazepine 10,11-epoxide intermediate by epoxide hydrolase and from oxcarbazepineviaa 10,11-dihydro-10-hydroxy carbamazepine intermediate.2,110,11-dihydro-10,11-dihydroxy Carbamazepine has been found in wastewater effluent.3

1.Franceschi, L., and Furlanut, M.A simple method to monitor plasma concentrations of oxcarbazepine, carbamazepine, their main metabolites and lamotrigine in epileptic patientsPharmacol. Res.51(4)297-302(2005) 2.Tybring, G., van Bahr, C., Bertilsson, L., et al.Metabolism of carbamazepine and its epoxide metabolite in human and rat liver in vitroDrug. Metab. Dispos.9(6)561-564(1981) 3.Miao, X.-S., Yang, J.-J., and Metcalfe, C.D.Carbamazepine and its metabolites in wastewater and in biosolids in a municipal wastewater treatment plantEnviron. Sci. Technol.39(19)7469-7475(2005)