A PEGylated building block
货号:ajcx28394
CAS:24991-53-5
分子式:(C2H4O)nC4H12N2O
分子量：0
溶解度:DMF: 33 mg/ml,DMSO: 33 mg/ml,Ethanol: 33 mg/ml,PBS (pH 7.2): 5 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PEG diamine is a PEGylated building block.^1,2It has been used as a linker to conjugate folic acid to 1,2-distearoyl-rac-glycero-PE (1,2-DSPE) as a component in the formation of doxorubicin-containing liposomes with anticancer activity.¹PEG diamine has also been conjugated to oleanolic acid , which improves oleanolic acid-induced inhibition of cell proliferation by 677-fold in HepG2 hepatocellular carcinoma cells.²

1.Lee, R.J., and Low, P.S.Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitroBiochim. Biophys. Acta1233(2)134-144(1995) 2.Jannus, F., Medina-O’Donnell, M., Rivas, F., et al.A diamine-PEGylated oleanolic acid derivative induced efficient apoptosis through a death receptor and mitochondrial apoptotic pathway in HepG2 human hepatoma cellsBiomolecules10(10)1375(2020)