规格: | 98% |
分子量: | 188.22 |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
Background:
Propargyl-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Andrew P. Crew, et al. Brm targeting compounds and associated methods of use. US20190300521A1.