Hydroxy-PEG2-acid是一种PROTAClinker，属于PEG类。可用于合成PROTAC分子。
货号:ajcx30784
CAS:1334286-77-9
分子式:C7H14O5
分子量：178.18
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.