Coumermycin A1 是一种 JAK2 信号激活剂。Coumermycin A1 抑制 DNA 旋转酶 (DNA Gyrase)，从而抑制细菌的细胞分裂。
货号:ajcx34644
CAS:4434-05-3
分子式:C55H59N5O20
分子量：1110.08
溶解度:DMSO : 50 mg/mL (45.04 mM; Need ultrasonic and warming)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria.

Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea leptin receptor mRNA level[1].

[1]. Tiantian Zhang, et al. SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes. Research Article.