Ganoderic acid Y 是一种 α-葡萄糖苷酶 (α-glucosidase) 抑制剂，对酵母 α-葡萄糖苷酶的 IC50 为170 μM。Ganoderic acid Y 通过阻止肠道病毒 71 (EV71) 的脱膜而抑制其复制。
货号:ajcx34794
CAS:86377-52-8
分子式:C30H46O3
分子量：454.68
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating[1][2].

Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71[2].

[1]. Chen XQ, et al. Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. Phytochemistry. 2018 May;149:103-115.
[2]. Zhang W, et al. Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochem Biophys Res Commun. 2014 Jul 4;449(3):307-12.