AGN210676是一种有效的选择性前列腺素EP2激动剂，EC50为5nM。详细信息请参考专利文献US20070203222A1中的化合物example23。
货号:ajcx12716
CAS:910562-15-1
分子式:C23H29NO5S
分子量：431.55
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.

AGN 210676 (Compound 23) also is a less potent agonist for recombinant human prostaglandin receptors hEP3A and hDP with EC50s of 153 nM and 7749 nM, respectively. AGN 210676 is useful for the treatment of glaucoma, ocular hypertension, inflammatory bowel disease, and the other diseases or conditions disclosed herein[1].

[1]. Old, David W, et al. SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS. US20070203222A1.