MCL-1/BCL-2-IN-3 (Compound 2) 是一种有效的选择性 Mcl-1 和 Bcl-2 抑制剂，IC50 分别为 5.95 和 4.78 μM。
货号:ajcx15640
CAS:2163793-55-1
分子式:C27H25BrN2O5S
分子量：569.47
溶解度:DMSO: 17.86 mg/mL (31.36 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively[1].

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.