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Phellopterin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phellopterin图片
规格:98%
分子量:300.31
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Phellopterin 是从 P. trifoliata 中分离得到的天然产物。Phellopterin 通过调节 Akt 和 PKC 通路降低 TNF-alpha 诱导的 VCAM-1 表达,从而抑制单核细胞与内皮细胞的粘附。
货号:ajcx15766
CAS:2543-94-4
分子式:C17H16O5
分子量:300.31
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Phellopterin is a natural product isolated from P. trifoliata. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].


[1]. Nizamutdinova IT, et al. Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. Int Immunopharmacol. 2008 May;8(5):670-8.