规格: | 98% |
分子量: | 424.3 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Background:
H-Gly-Arg-pNA is a colorimetric substrate for thrombin.1,2 Thrombin preferentially binds to and cleaves the Gly-Arg (GR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.
参考文献
1. Hortin, G.L., Warshawsky, I., and Laude-Sharp, M. Macromolecular chromogenic substrates for measuring proteinase activity. Clin. Chem. 47(2), 215-222 (2001).
2. Rijkers, D.T., Wielders, S.J., Tesser, G.I., et al. Design and synthesis of thrombin substrates with modified kinetic parameters. Thromb. Res. 79(5-6), 491-499 (1995).