包装: | 50mg |
规格: | 98% |
市场价: | 1017元 |
分子量: | 220.3 |
Background:
CAY10621 is an inhibitor of sphingosine kinase 1 (SPHK1; IC50= 3.3 μM).1It is selective for SPHK1 over SPHK2 at 10 μM and PKC at concentrations less than 100 μM. CAY10621 inhibits SPHK1 activity by 70% in U937 cells when used at a concentration of 5 μM.
1.Wong, L., Tan, S.L., Lam, Y., et al.Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinasesJournal of Medicinal Chemistry523618-3626(2009)