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Arachidonic Acid-d8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Arachidonic Acid-d8图片
规格:98%
分子量:312.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An internal standard for the quantification of arachidonic acid
货号:ajcx21708
CAS:69254-37-1
分子式:C20H24D8O2
分子量:312.5
溶解度:0.1 M Na2CO3: 1.7 mg/ml,DMF: >100 mg/ml,DMSO: >100 mg/ml,Ethanol: Miscible
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Arachidonic acid-d8contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of arachidonic acid by GC-or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.1Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.2


1.Burgoyne, R.D., and Morgan, A.The control of free arachidonic acid levelsTrends Biochem. Sci.15(10)365-366(1990) 2.Nixon, A.B., Greene, D.G., and Wykle, R.L.Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophilsBiochim. Biophys. Acta.1300(3)187-196(1996)