An agonist of GluR5
货号:ajcx21742
CAS:N/A
分子式:C10H16N2O4.XH2O
分子量：228.2
溶解度:Water: 10 mM
纯度：98%
存储：Store at -20°C
库存：现货

Background:

ATPA is an agonist of ionotropic glutamate receptor 5 (GluR5/GluK1; K_i= 0.0043 µM).¹It is selective for GluR5 over GluR1-4 (K_is = 6-14 µM), as well as GluR6 (K_i= >1,000 µM). ATPA induces inward currents in HEK293 cells expressing recombinant human GluR5 and isolated rat dorsal root ganglion (DRG) neurons (EC₅₀s = 2.1 and 0.6 µM, respectively).

1.Clarke, V.R., Ballyk, B.A., Hoo, K.H., et al.A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmissionNature389(6651)599-603(1997)