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JWH 019 N-(5-hydroxyhexyl)metabolite-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
JWH 019 N-(5-hydroxyhexyl)metabolite-d5图片
规格:98%
分子量:376.5
包装与价格:
包装价格(元)
100ug电议
500ug电议
1mg电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx22718
CAS:N/A
分子式:C25H20D5NO2
分子量:376.5
溶解度:DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 20 mg/ml,Ethanol: 5 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

JWH 019 N-(5-hydroxyhexyl) metabolite-d5contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of acetyl norfentanyl by GC-or LC-mass spectrometry. JWH 019 N-(5-hydroxyhexyl) metabolite-d5contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of acetyl norfentanyl by GC-or LC-mass spectrometry. Cannabimimetic indoles, including certain JWH compounds, have been identified in herbal blends. JWH 018, a potent agonist of both the central cannabinoid (CB1) receptor and peripheral cannabinoid (CB2) receptor, has been found in many herbal blends and has been regulated in the United States and other countries. Studies indicate that JWH 018 is rapidly metabolized by the liver and that certain metabolites can be identified in the urine.1,2,3JWH 019 is nearly identical to JWH 018 in structure and activity at both CB receptors.4JWH 019 N-(5-hydroxyhexyl) metabolite is an expected metabolite of JWH 019, detectable both in serum and urine. Its biological activities have not been evaluated.


1.Teske, J., Weller, J.P., Fieguth, A., et al.Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometryJournal of Chromatography B8782659-2663(2010) 2.Sobolevsky, T., Prasolov, I., and Rodchenkov, G.Detection of JWH-018 metabolites in smoking mixture post-administration urineForensic Sci. Int.200(1-3)141-147(2010) 3.Wintermeyer, A., MÖller, I., Thevis, M., et al.In vitro phase I metabolism of the synthetic cannabimimetic JWH-018Anal. Bioanal. Chem.398(5)2141-2153(2010) 4.Aung, M.M., Griffin, G., Huffman, J.W., et al.Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor bindingDrug Alcohol Depend.60(2)133-140(2000)