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N-Despropyl Ropinirole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Despropyl Ropinirole图片
规格:98%
分子量:218.3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
An active metabolite of ropinirole
货号:ajcx25322
CAS:106916-16-9
分子式:C13H18N2O
分子量:218.3
溶解度:DMF: 25 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

N-Despropyl ropinirole is an active metabolite of the dopamine D2receptor agonist ropinirole .1It increases extracellular acidification rates in CHO cells expressing human dopamine D2, D3, and D4receptors (EC50s = 0.63, 0.063, and 1.23 µM, respectively). N-Despropyl ropinirole is also a potential impurity found in commercial preparations of ropinirole.2


1.Coldwell, M.C., Boyfield, I., Brown, T., et al.Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cellsBr. J. Pharmacol.127(7)1696-1702(1999) 2.Coufal, P., Stulik, K., Claessens, H.A., et al.Separation and quantification of ropinirole and some impurities using capillary liquid chromatographyJ. Chromatogr. B Biomed. Sci. Appl.732(2)437-444(1999)