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Ganoderol B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ganoderol B图片
规格:98%
分子量:440.7
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Ganoderol B 是一种有效的 α-葡萄糖苷酶抑制剂。
货号:ajcx25422
CAS:104700-96-1
分子式:C30H48O2
分子量:440.7
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Ganoderol B is a triterpenoid that has been found inG. lucidumand has diverse biological activities.1,2,3,4,5It inhibits angiotensin-converting enzyme (ACE) and α-glucosidase (IC50s = 220 and 119.8 µM, respectively).1,2Ganoderol B is cytotoxic to HGC-27 gastric, HeLa cervical, and A549 lung cancer cells (IC50s = 16.15, 12.64, and 9.77 µM, respectively).3It prevents herpes simplex virus 1 (HSV-1) infection in Vero cells (EC50= 68 µM).4Ganoderol B (0.001 and 0.1 mg/kg) reduces testosterone-induced increases in ventral prostate weight in castrated rats.5


1.Morigiwa, A., Kitabatake, K., Fujimoto, Y., et al.Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidumChem. Pharm. Bull. (Tokyo)34(7)3025-3028(1986) 2.Fatmawati, S., Shimizu, K., and Kondo, R.Ganoderol B: A potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidumPhytomedicine18(12)1053-1055(2011) 3.Su, H.-G., Zhou, Q.-M., Guo, L., et al.Lanostane triterpenoids from Ganoderma luteomarginatum and their cytotoxicity against four human cancer cell linesPhytochemistry15689-95(2018) 4.Mothana, R.A.A., Ali, N.A.A., Jansen, R., et al.Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferiFitoterapia74(1-2)177-180(2003) 5.Liu, J., Shimizu, K., Konishi, F., et al.The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidumBioorg. Med. Chem.15(14)4966-4972(2007)