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Salicylic Acid-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Salicylic Acid-d4图片
规格:98%
分子量:142.1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
An internal standard for the quantification of salicylic acid
货号:ajcx25910
CAS:78646-17-0
分子式:C7H2D4O3
分子量:142.1
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:


Salicylic acid-d4is intended for use as an internal standard for the quantification of salicylic acid by GC- or LC-MS. Salicylic acid is an active metabolite of the COX inhibitor aspirin and a plant hormone that has been found inCucumis sativus.1,2It protectsCucumis sativusleaves from infection byS. fuligineaorE. cichoracearumwhen used at a concentration of 10 mM, as well as inhibitsA. thalianaroot growth at 0.3 mM.2,3Salicylic acid (1 and 4 mM) reduces IFN-γ- and TNF-α-induced increases inNOS2expression in primary rat cardiac fibroblasts.4It decreases urine prostaglandin E2levels in dogs when administered at a dose of 40 mg/kg.5


1.Klessig, D.F.Newly identified targets of aspirin and its primary metabolite, salicylic acidDNA Cell Biol.35(4)163-166(2016) 2.Feussner, I., Fritz, I.G., Hause, B., et al.Induction of a new lipoxygenase form in cucumber leaves by salicylic acid or 2,6-dichloroisonicotinic acidBot. Acta110(2)101-108(1997) 3.Kim, T.-H., Kunz, H.-H., Bhattacharjee, S., et al.Natural variation in small molecule-induced TIR-NB-LRR signaling induces root growth arrest via EDS1- and PAD4-complexed R protein VICTR in ArabidopsisPlant Cell24(12)5177-5192(2012) 4.Farivar, R.S., and Brecher, P.Salicylate is a transcriptional inhibitor of the inducible nitric oxide synthase in cultured cardiac fibroblastsJ. Biol. Chem.271(49)31585-31592(1996) 5.Zambraski, E.J., Atkinson, D.C., and Diamond, J.Effects of salicylate vs. aspirin on renal prostaglandins and function in normal and sodium-depleted dogsJ. Pharmacol. Exp. Ther.247(1)96-103(1988)