| 规格: | 98% |
| 分子量: | 373.44 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
Background:
TCO-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.
m.cnreagent.com