包装: | 100mg |
规格: | 98% |
市场价: | 801元 |
分子量: | 284.35 |
Background:
BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1.