Omzotirome (TRC150094) 是一种碘甲状腺原氨酸的功能类似物，可用于高脂血症的研究 (WO2008149379)。
货号:ajcx37282
CAS:1092551-88-6
分子式:C19H24N2O3
分子量：328.41
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Omzotirome (TRC150094), a functional analog of iodothyronines, can be used for the research of hyperlipidaemia (WO2008149379)[1][2].

Omzotirome (0.750 mg/ 100 g; i.p.) with high-fat diet rats have significantly less visceral adipose tissue (vs. HFD rats) and exhibit altered metabolism in two major tissues that are very active metabolically and exhibit increased energy expenditure and body weight (BW) gain comparable to that of standard chow-fed rats[1].Omzotirome, a functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet (HFD)[1].

[1]. WO2008149379
[2]. Cioffi F, et al. TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet. FASEB J. 2010;24(9):3451-3461.