c(phg-isoD-G-R-(NMe)k) TFA 是有效选择性的 α5β1 整合素 配体，IC50 为 2.9 nM。
货号:ajcx14364
CAS:N/A
分子式:C29H42F3N9O9
分子量：717.69
溶解度:DMSO: 250 mg/mL (348.34 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

c(phg-isoD-G-R-(NMe)k) TFA is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM[1].

c(phg-isoD-G-R-(NMe)k) TFA is trimerized with the chelator TRAP and used as a positron-emission tomography tracer for monitoring α5β1 integrin expression in a M21 mouse xenograft[1].

[1]. Kapp TG, et al. N-Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent. J Med Chem. 2018 Mar 22;61(6):2490-2499.