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Oregon Green? 488
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oregon Green? 488图片
规格:98%
分子量:368.3
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
A fluorinated fluorescein dye
货号:ajcx26178
CAS:195136-58-4
分子式:C20H10F2O5
分子量:368.3
溶解度:Chloroform: soluble,DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:


Oregon Green?488 is a fluorinated fluorescein dye.1,2It exists as a tautomer in aqueous solutions.2Oregon Green?488 has minimal pH dependence at physiological pH but it can be used as an indicator for intracellular pH due to its low pKa of 4.8.2,3It is less susceptible to photobleaching than fluorescein. Oregon Green?488 has been conjugated to antibodies and proteins, as well as DNA, for use in labeling and detection.2,4,3It displays excitation/emission maxima of 490/514 nm, respectively.1


1.Sun, W.-C., Gee, K.R., Klaubert, D.H., et al.Synthesis of fluorinated fluoresceinsJ. Org. Chem.62(19)6469-6475(1997) 2.Orte, A., Crovetto, L., Talavera, E.M., et al.Absorption and emission study of 2’,7’-difluorofluorescein and its excited-state buffer-mediated proton exchange reactionsJ. Phys. Chem. A.109(5)734-747(2005) 3.Leung, K., Chakraborty, K., Saminathan, A., et al.A DNA nanomachine chemically resolves lysosomes in live cellsNat. Nanotechnol.14(2)176-183(2019) 4.Yu, P., Lasagna, M., Pawlyk, A.C., et al.IIAGlc inhibition of glycerol kinase: A communications network tunes protein motions at the allosteric siteBiochemistry46(43)12355-12365(2007)