5,7-Dimethoxyflavone是Kaempferiaparviflora的主要成分之一，具有抗肥胖，抗炎和抗肿瘤作用。5,7-Dimethoxyflavone抑制细胞色素P450(CYP)3As。5,7-Dimethoxyflavone也是有效的抗乳腺癌蛋白(BCRP)抑制剂。
货号:ajcx32506
CAS:21392-57-4
分子式:C17H14O4
分子量：282.29
溶解度:DMSO: 100 mg/mL (354.25 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].

[1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614. [2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34.