您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > PSB-1011 sodium
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PSB-1011 sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:4499-01-8
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
50mg电议
500mg电议

产品介绍

PSB-1011 is a competitive inhibitor of the rat P2X2 receptor with a Ki of 79 nM. PSB-1011 exhibited a competitive mechanism of action (pA(2) 7.49). It was >100-fold selective versus P2X4, P2X7, and several investigated P2Y receptor subtypes (P2Y(2,4,6,12)); selectivity versus P2X1 and P2X3 receptors was moderate (>5-fold). PSB-1011 was >13-fold more potent at the homomeric P2X2 than at the heteromeric P2X2/3 receptor. References: Hausmann R, Schmalzing G. P2X1 and P2X2 receptors in the central nervous system as possible drug targets. CNS Neurol Disord Drug Targets. 2012 Sep;11(6):675-86. Review. PubMed PMID: 22963438.

纯度:≥98%

CAS:4499-01-8