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RO-7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RO-7图片
规格:98%
分子量:487.49
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
RO-7是甲型和乙型流感病毒的二代聚合酶PA亚基内切核酸酶抑制剂。
货号:ajcx12768
CAS:1370241-45-4
分子式:C24H20F3N3O3S
分子量:487.49
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.

RO-7 is a compound that potently inhibits influenza virus replication and belongs to a new class of drugs in late-stage clinical trials for treatment of influenza virus infection. RO-7 displays broad-spectrum anti-influenza activity in vitro and protects mice from lethal challenge with both influenza A and B viruses[1].

RO-7 protects mice from lethal challenge with both influenza A and B viruses[1].

[1]. Jones JC, et al. Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation InfluenzaVirus Endonuclease Inhibitors. MBio. 2018 Apr 24;9(2). pii: e00430-18.