规格: | 98% |
分子量: | 624.72 |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
Background:
Target Protein-binding moiety 13 is a synthetic ligand for FKBP (SLF), which is used in the synthesis of PROTACs.
Target Protein-binding moiety 13 (SLF building block 2) is a synthetic ligand for FKBP (SLF). SLF is composed of only one half of FK506 and it is known to have a significantly weaker affinity for FKBP12.
[1]. Dunyak BM, et al. Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of TwoIntracellular Proteins. ACS Chem Biol. 2015 Nov 20;10(11):2441-7.