An internal standard for the quantification of PAF C16
货号:ajcx23202
CAS:211106-54-6
分子式:C26H50D4NO7P
分子量：527.7
溶解度:DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS pH 7.2: 25 mg/ml,Water: 30 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PAF C-16-d₄contains four deuterium atoms at the 7, 7', 8, and 8' positions of the hexadecyl moiety. It is intended for use as an internal standard for the quantification of PAF C-16 by GC-or LC-mass spectrometry. PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways.¹It is a potent mediator of neutrophil migration,²the production of reactive oxygen species,³and IL-6⁴in human macrophages. It is a more potent mediator of platelet aggregation than PAF C-18⁵. Pathological processes involving PAF include necrotizing enterocolitis,⁶inflammation, asthma, and allergy.⁷

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