规格: | 98% |
分子量: | 612.7 |
包装 | 价格(元) |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Background:
Z-FR-AMC is a fluorogenic substrate for cathepsin L.1Upon enzymatic cleavage by cathepsin L, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin L activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
1.Carmona, C., Dowd, A.J., Smith, A.M., et al.Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juvenilesMol. Biochem. Parasitol.62(1)9-17(1993)