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Protriptyline hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1225-55-4
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
50mg电议
500mg电议

产品介绍

Protriptyline Hydrochloride is a tricyclic secondary amine with antidepressant property. Protriptyline hydrochloride blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. Protriptyline does not block dopamine transport but may have an indirect dopamine-facilitating effect through interactions of increased peri-synaptic abundance of norepinephrine, particularly in the cerebral cortex, where adrenergic terminals exceed dopaminergic terminals. This results in elevation of mood and behaviorally bioavailable activity. In addition, this agent exhibits anticholinergic activity. References: Chang HT, Chou CT, Yu CC, Tsai JY, Sun TK, Liang WZ, Lin KL, Tseng HW, Kuo CC, Chen FA, Kuo DH, Pan CC, Ho CM, Shieh P, Jan CR. The mechanism of protriptyline-induced Ca2+ movement and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. J Recept Signal Transduct Res. 2015;35(5):429-34. doi: 10.3109/10799893.2014.1000464. Epub 2015 Jun 22. PubMed PMID: 26096164.

纯度:≥98%

CAS:1225-55-4